EPFLx: Fundamentals of Biomedical Imaging: Ultrasounds, X-ray, positron emission tomography (PET) and applications

EPFLx: Fundamentals of Biomedical Imaging: Ultrasounds, X-ray, positron emission tomography (PET) and applications

by École polytechnique fédérale de Lausanne

Fundamentals of Biomedical Imaging: Ultrasound, X-ray, and PET Scanning

Course Description

Welcome to "Fundamentals of Biomedical Imaging: Ultrasound, X-ray, and PET Scanning," an advanced physics course that delves into the fascinating world of in vivo bio-imaging modalities. This comprehensive course explores the physical principles behind major imaging techniques used in modern medicine and life sciences. From the gentle waves of ultrasound to the penetrating power of X-rays and the molecular precision of Positron Emission Tomography (PET), you'll gain a deep understanding of how these technologies work and their applications in healthcare and research.

What Students Will Learn

  • The main imaging concepts that define image quality, including Signal-to-Noise Ratio (SNR) and Contrast-to-Noise Ratio (CNR)
  • The fundamental principles of ultrasound, X-ray imaging (CT), Single-Photon Emission Computed Tomography (SPECT), and Positron Emission Tomography (PET)
  • Factors that limit image quality in each technique
  • Typical applications of these imaging modalities in real-world scenarios
  • How to recognize and distinguish between different imaging techniques based on their output

Pre-requisites

  • Completed introductory physics at the Bachelor level
  • Familiarity with the concept of Fourier transformation
  • A strong interest in the intersection of physics, biology, and medical sciences

Course Coverage

  • Introduction to bio-imaging and its importance in modern medicine
  • Ultrasound imaging principles and applications
  • Ionizing radiation and X-ray generation
  • X-ray imaging and tissue interaction
  • Computed Tomography (CT) - from projection to image reconstruction
  • Emission Tomography and tracer principles
  • Positron Emission Tomography (PET) - imaging antimatter annihilation
  • Tracer kinetics and modeling of imaging data
  • Biological safety considerations in medical imaging

Who This Course Is For

  • Engineering students specializing in biomedical technologies
  • Physics students interested in medical applications
  • Medical students seeking a deeper understanding of imaging technologies
  • Researchers in life sciences looking to expand their knowledge of bio-imaging
  • Professionals in the medical imaging industry aiming to broaden their expertise

Real-World Applications

  • Assisting in the development of new imaging technologies
  • Improving existing imaging protocols in clinical settings
  • Interpreting and analyzing medical images more effectively
  • Contributing to research in fields such as neuroscience, oncology, and cardiology
  • Enhancing patient care through better understanding of diagnostic tools
  • Participating in interdisciplinary teams working on cutting-edge medical technologies

Syllabus

  1. Introduction to the course, importance and essential elements of bio-imaging
  2. Ultrasound imaging; ionizing radiation and its generation
  3. X-ray imaging - when the photon bumps into living tissue, radioprotection primer
  4. Computed tomography - from projection to image
  5. Emission tomography - what are tracers and how to trace them in your body, x-ray detection, scintillation principle
  6. Positron emission tomography (PET) - imaging anti-matter annihilation
  7. Tracer kinetics - modeling of imaging data

By enrolling in this course, you'll embark on an exciting journey through the world of biomedical imaging, gaining valuable insights that bridge the gap between physics and life sciences. Don't miss this opportunity to expand your understanding of these crucial technologies and their impact on modern healthcare and research!

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