GeorgetownX: Demystifying Biomedical Big Data: A User’s Guide

GeorgetownX: Demystifying Biomedical Big Data: A User’s Guide

by Georgetown University

Demystifying Biomedical Big Data: A User's Guide

An intermediate-level course offered by GeorgetownX

Course Description

"Demystifying Biomedical Big Data: A User's Guide" is designed to empower professionals and students in the biomedical field with limited bioinformatics experience. This comprehensive course aims to bridge the gap between the ever-growing volume of biomedical data and the ability to effectively analyze and interpret it for scientific discoveries and patient care.

What You Will Learn

  • Understanding the generation and processing of biomedical data
  • Exploring various biomedical big data resources (e.g., TCGA, G-DOC, UNIPROT)
  • Analyzing genomic, transcriptomic, and proteomic data using online tools
  • Utilizing systems biology resources and tools to make sense of big data
  • Appreciating the value of big data in biomedical research and clinical practice

Prerequisites

While not strictly required, a background in biology (high school or undergraduate level) is suggested. Students are encouraged to review relevant courses in biology and life sciences, including genetics, genomics, DNA/RNA/Protein structure and function, transcription, and translation.

Course Content

  • Introduction to bioinformatics platforms and resources
  • Translational research and big data
  • DNA and big data analysis (copy number, genome sequencing)
  • RNA and big data analysis (gene expression, microRNA)
  • Protein analysis and big data
  • Systems biology and big data integration
  • Regulatory issues related to biomedical big data
  • Perspectives from experts in the field

Who Should Take This Course

  • Biomedical researchers and scientists
  • Healthcare professionals
  • Students in biology, medicine, or related fields
  • Anyone interested in understanding and leveraging biomedical big data

Real-World Applications

  • Conduct more effective biomedical research by leveraging big data resources
  • Improve patient care through data-driven decision-making
  • Contribute to precision medicine initiatives
  • Collaborate more effectively with bioinformaticians and data scientists
  • Stay current with the latest trends in biomedical data analysis
  • Apply data analysis techniques to your own research or clinical practice

Syllabus

Week 1: Introduction and Overview of Bioinformatics Platforms and Resources
Week 2: Translational Research and Big Data
Week 3: DNA and Big Data
Week 4: RNA and Big Data
Week 5: Proteins and Big Data Part I
Week 6: Proteins and Big Data Part II
Week 7: Systems Biology and Big Data
Week 8: Perspectives from the Field and Course Conclusion

Each week includes lectures, demonstrations, and hands-on exercises to reinforce learning and practical application of the concepts covered.

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