MDAndersonX: CERTaIN: Pragmatic Clinical Trials and Healthcare Delivery Evaluations

MDAndersonX: CERTaIN: Pragmatic Clinical Trials and Healthcare Delivery Evaluations

by The University of Texas MD Anderson Cancer Center in Houston

This course provides an in-depth look into pragmatic clinical trials and their complexities, covering essential aspects of clinical research design, approval processes, and data analysis. Experts in the field will guide learners through the critical decisions necessary when organizing clinical studies, including power and sample size calculations and advanced trial designs such as Bayesian and adaptive trials.

  • Understanding of various clinical trial designs, specifically pragmatic clinical trials
  • Ability to identify and apply different clinical trial designs and analyze their data
  • Proficiency in statistical methods relevant to pragmatic trials

An introductory course on clinical trials (CERTaIN.1x) is recommended but not a compulsory prerequisite for this course. A basic understanding of clinical research terminologies and methodologies would be beneficial.

  • Exploration of different clinical trial designs, including Bayesian and adaptive trials
  • Step-by-step guide through the research approval process
  • Detailed instruction on conducting power and sample size calculations
  • Insights into more complex study designs used in research

Researchers interested in expanding their knowledge on pragmatic clinical trials, comparative effectiveness research (CER), and patient-centered outcomes research (PCOR) will find this course especially beneficial.

Learners can apply the skills acquired from this course in various aspects of clinical research, from designing and handling the complexities of pragmatic trials to implementing advanced statistical methods for robust data analysis. These capabilities are essential for conducting scientifically sound and ethical research that can influence health policies and patient care practices.

  1. Overview of Design Options for Pragmatic Clinical Trials
  2. Outcome Measures in Clinical Trials
  3. Non-inferiority Trials
  4. Basic Analytic Methods
  5. Basic Power and Sample Size Calculations
  6. SMART: Adaptive Treatment Strategies
  7. Introduction to Bayesian Methods
  8. Bayesian Designs
  9. Quasi-Experiment in Health Services Research
  10. Adaptive Trial Design
  11. Logistics of Clinical Trials
Course Page   MDAndersonX: CERTaIN: Pragmatic Clinical Trials and Healthcare Delivery Evaluations